Neu CD8-ECD, SFCI21Thy2D3, 0.5 mL, ASR in Krefeld, Nordrhein-Westfalen, Deutschland
Neu
Spezifikationen
- Zustand
- neu
- Target species
- Human
- Specificity
- CD8
- Other names
- CD8, T8 antigen
- Fluorochrome
- ECD
- Regulatory status
- ASR
- Size
- 0.5 mL
- Format
- Liquid
- Flow product line
- cyto-stat
- Clone
- SFCI21Thy2D3
- Isotype
- IgG1 Mouse
- Clone description
- SFCI21Thy2D3 monoclonal antibody recognizes the α chain of the CD8 molecule.
- Cross reactivity
- SFCI21Thy2D3 cross reacts with: Common Marmoset.
- Volume
- 0.5 mL
- Kategorie
- Laborausstattung in Deutschland
- Subkategorie
- Reagenzien
- Subkategorie 2
- Instruments
- Subkategorie 3
- Lab equipment
- Subkategorie 4
- Durchflusszytometrie
- Inserat-ID
- 100958701
Beschreibung
Product No:
6604728
The CD8 antigen is a disulfide-linked dimer, which exists either as a CD8α homodimer or as a CD8α/β heterodimer. CD8α is required for surface expression of CD8β. The molecular weight of each monomer of α or β is approximately 32-34 kDa. CD8 binds to a non-polymorphic domain (α3 domain) of MHC Class I molecules. CD8 is expressed on a subset of human peripheral blood T lymphocytes. A subset of NK cells possess the CD8 antigen but show low to medium density of expression. CD8α homodimer is expressed by NK cells and γ/δ+ T cells. CD8 is also present on most thymocytes where it is frequently co-expressed with CD4, and on a subpopulation of bone marrow cells. The CD8 molecule acts with the T Cell Receptor (TCR) as a coreceptor for MHC class I restricted antigen recognition. CD8 is widely used as a marker of cytotoxic T lymphocytes.
List Price -