Neu HLA-ABC-FITC, B9.12.1, 2 mL, ASR in Krefeld, Nordrhein-Westfalen, Deutschland
Neu
Spezifikationen
- Zustand
- neu
- Target species
- Human
- Specificity
- HLA-ABC
- Other names
- HLA Class I, HLA-ABC
- Fluorochrome
- FITC
- Regulatory status
- ASR
- Size
- 2 mL
- Format
- Liquid
- Flow product line
- IOTest
- Clone
- B9.12.1
- Isotype
- IgG2a Mouse
- Clone description
- The B9.12.1 monoclonal antibody recognizes a monomorphic epitope common to HLA-A, -B and -C molecules. B9.12.1 antibody does not recognize unassociated heavy chains.
- Cross reactivity
- B9.12.1 cross reacts with: Cynomolgus Monkey, Indian Rhesus, Olive Baboon.
- Volume
- 2 mL
- Kategorie
- Laborausstattung in Deutschland
- Subkategorie
- Reagenzien
- Subkategorie 2
- Instruments
- Subkategorie 3
- Lab equipment
- Subkategorie 4
- Durchflusszytometrie
- Inserat-ID
- 99921732
Beschreibung
Product No:
IM1838U
HLA-A, -B, and -C are major histocompatibility complex (MHC)-class I antigens. Like other class I molecules (i.e. HLA-E, -F, -G), HLA-A, -B, and -C are heterodimers consisting of a 40 – 45 kDa transmembrane glycoproteic α-chain, noncovalently combined to the invariant β2-microglobulin. All class I molecules have conserved, monomorphic domains, but are also characterized by their extensive degree of allelic polymorphism. MHC molecules play a central role in the immune response. They are involved in the maturation of T cell repertoire, in the activation of T lymphocytes by presentation of xenogenic peptides or in the allogenic response. HLA-A, -B and -C are "classical" MHC Class I molecules and are expressed on the surface of most nucleated human cell types.
€507.40
List Price - €507.40
$592 USD